Paper Title :Design and Fabrication of Stimulated Bioreactors For Neural Stem Cell Engineering (Simbion Project)
Author :Yudan Whulanza, Ignasius Dwi Sagita, Hanif Nadhif, Nurhadi Ibrahim
Article Citation :Yudan Whulanza ,Ignasius Dwi Sagita ,Hanif Nadhif ,Nurhadi Ibrahim ,
(2017 ) " Design and Fabrication of Stimulated Bioreactors For Neural Stem Cell Engineering (Simbion Project) " ,
International Journal of Mechanical and Production Engineering (IJMPE) ,
pp. 38-43,
Volume-5,Issue-1
Abstract : Microfluidic bioreactor gives a unique environment for culturing cells with its perfusion flow as a growth
stimulant. This microenvironment was made of polydimethylsiloxane (PDMS) that offers a high biocompatibility and low
toxicity. This bioreactor was made of polydimethylsiloxane (PDMS). It offers an opportunity to overcome previous
limitations and recreate critical elements of in vivo microenvironment in order to investigate cellular responses. A dynamic
flow of liquid media is employed to mimic the in vivo ambient. Here, we developed bioreactors that equipped with electrical
stimulant for neural cells. This paper investigates the fluid dynamic study specifically the shear rate that generated during the
flow. Ultimately, this system enables us to observe the interaction between cell and the stimulant.
Keywords- microfluidic bioreactor, growth stimulant, microenvironment, neural cell
Type : Research paper
Published : Volume-5,Issue-1
DOIONLINE NO - IJMPE-IRAJ-DOIONLINE-6758
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Copyright: © Institute of Research and Journals
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Published on 2017-03-09 |
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